4 Supplements to Avoid: From Liver Damage to Digestive Issues (2026)

Unveiling the Dark Side of Supplements: 4 Surprising Health Risks

Are you aware that some supplements can be more harmful than beneficial? While supplements are often marketed as a quick fix for health issues, they can sometimes lead to unexpected consequences. From digestive issues to liver damage, some supplements can have serious side effects. In this article, we'll explore four supplements that you should avoid due to their potential health risks.

Kava: A Stress Reliever with a Dark Side

Kava, a plant native to Oceania, has been used for centuries to ease stress and anxiety. Its supplements are available in various forms, including capsules, tablets, powders, teas, and liquid extracts. However, the use of kava has been banned in several countries due to its potential health risks. A 2012 study found that kava contains natural aflatoxins, which can be toxic to the human liver. In 2018, there were approximately 100 reported cases of liver damage from kava. Additionally, kava can slow down the nervous system, increasing the risk of impairment when combined with alcohol or anxiety medications. The FDA has deemed the beverage form of kava 'not safe for human consumption'.

Kratom: A Popular Pain Reliever with Serious Side Effects

Kratom, made from the leaves of a tropical tree native to Southeast Asia, has gained popularity as a natural pain reliever and mood booster. According to a 2025 nationally representative survey, 9% of American adults reported using Kratom. However, the FDA has issued a warning against its use, citing potential liver toxicity, seizures, substance use disorder (SUD), and even death in some cases. The agency emphasizes that Kratom is not suitable for use as a dietary supplement and should be avoided, especially by children.

St. John's Wort: An Uneffective Antidepressant with Drug Interactions

St. John's Wort is often marketed as a natural antidepressant, but research suggests that it has no significant improvements in depression. A 2001 clinical trial reported in JAMA found that the herb does not work and has the same effects as a placebo. Moreover, St. John's Wort can interact with numerous medications, including birth control pills, immunosuppressant drugs, and heart medications such as warfarin, making them ineffective. It's crucial to consult with a healthcare professional before adding St. John's Wort to your regimen.

Green Tea Extract: A Weight Loss Supplement with Toxic Side Effects

Green tea is a popular beverage and weight loss supplement, but its extract can have toxic side effects. According to David Seres, MD, of Columbia University Medical Center, drinking 12 cups of green tea throughout the day is not the same as taking green tea extract, which can cause digestive issues and interact with medications such as blood thinners and statins for cholesterol. The US National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) warns that green tea extract has been linked with severe liver damage, requiring transplant or leading to death. When it comes to supplements, more is not better, and it's essential to consult with a healthcare professional before adding any to your routine.

So, the next time you're considering a new supplement, remember to weigh the risks and benefits carefully. Your health is worth it!

4 Supplements to Avoid: From Liver Damage to Digestive Issues (2026)
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